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KMID : 0882420140870010072
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Korean Journal of Medicine
2014 Volume.87 No. 1 p.72 ~ p.76
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A Case of Life-Threatening Supraventricular Tachycardia Related to Flecainide Toxicity
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Cheon Sang-Soo
Song Joon-Hyuk
Bae Myung-Hwan
Lee Jang-Hoon
Yang Dong-Heon
Park Hun-Sik
Chae Shung-Chul
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Abstract
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Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal failure. Electrical and hemodynamic deterioration during flecainide toxicity may not respond to conventional treatments. We report the successful management of flecainide toxicity using extracorporeal membrane oxygenation (ECMO), hemoperfusion, and bicarbonate administration maintaining alkalinity.
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KEYWORD
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Flecainide, Hemoperfusion, Extracorporeal membrane oxygenation
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